Lipids Online News
- July 4, 2008
- Women have less LV hypertrophy regression with antihypertensives than men
- Women experience less left ventricular hypertrophy regression with antihypertensive therapy than men, study findings indicate. [Hypertension 2008; 52: 100-106]
- Serum fatty acid composition is associated with CRP concentration in elderly
- A fatty acid profile reflecting high saturated fat intake correlates positively with C-reactive protein concentrations in the elderly, show results from the Prospective Investigation of the Vasculature in Uppsala Seniors study.
[Atherosclerosis 2008; Advance online publication]
- Associations of four genetic variants and CHD confirmed in FH population
- Scientists have confirmed previously discovered associations between four genetic polymorphisms and coronary heart disease in a population of individuals with familial hypercholesterolemia. [Eur Heart J 2008; Advance online publication]
- Lp(a) predicts carotid stenosis and occlusion, but not carotid plaque area
- Lipoprotein (Lp)(a) is a significant independent predictor for carotid stenosis and occlusion, but not carotid plaque area, report investigators. [Arterioscler Thromb Vasc Biol 2008; Advance online publication]
- July 3, 2008
- DSCT-CA 'reliably rules out in-stent restenosis'
- Dual-source computed tomography coronary angiography reliably rules out in-stent restenosis in cardiac patients, Dutch researchers report. [Heart 2008; 94: 848-854]
- Removal of oxLDL dramatically improves atherosclerotic prognosis in mice
- Researchers report that removal of oxidized low-density lipoprotein from the circulation of mice almost completely halts atherosclerotic progression compared with controls. [Circulation 2008; 118: 75-83]
- Childhood BMI better predictor than age at menarche for later CVD risk
- High childhood body mass index rather than early age at menarche appears to predict high adult BMI and associated cardiovascular disease risk, report investigators. [Am J Clin Nutr 2008; 87: 1876-1882]
- Chromosome 6 and 12 loci associated with lipid levels in Samoans
- Scientists have found evidence for genetic linkage to low-density lipoprotein cholesterol and the total cholesterol to LDL cholesterol ratio on chromosomes 6p and 12q in Samoan individuals. [J Lipid Res 2008; Advance online publication]
- July 2, 2008
- Link between CVD risk and high Lp(a) is weakened by HRT
- Researchers report that the previously observed relationship between high lipoprotein (Lp)(a) and increased risk for cardiovascular disease is weakened in women taking hormone replacement therapy. [J Am Coll Cardiol 2008; 52: 124-131, 132-134]
- High oxLDL linked to overweight and obesity and low serum carotenoids
- Older women who are overweight or obese, or who have low serum carotenoids, have higher levels of oxidized low-density lipoprotein than those of normal weight and carotenoid levels, show study results. [Nutrition 2008; Advance online publication]
- Hypothyroidism not associated with increase in carotid atherosclerosis
- The presence of hypothyroidism in hyperlipidemic patients does not significantly increase their risk for carotid atherosclerosis, investigators report in the journal Atherosclerosis. [Atherosclerosis 2008; Advance online publication]
- July 1, 2008
- Low HDL cholesterol increases risk for memory problems in middle age
- Low levels of high-density lipoprotein cholesterol are associated with memory deficit and decline in middle-aged individuals, report investigators in the journal Arteriosclerosis, Thrombosis, and Vascular Biology. [Arterioscler Thromb Vasc Biol 2008; Advance online publication]
- Low CRF linked to adverse inflammatory and lipid profile in Type 2 diabetes
- Men with Type 2 diabetes and low levels of cardiorespiratory fitness have high levels of inflammatory markers, fibrinolytic factors, and lipoprotein (Lp)(a), show study results.
[Am J Cardiol 2008; Advance online publication]
- NAFLD in obese children is strongly linked to adverse CV risk profile
- Overweight and obese children with non-alcoholic fatty liver disease have a significantly more adverse cardiovascular risk profile than children of a similar weight without NAFLD, report scientists. [Circulation 2008; Advance online publication]
- Negative affect linked to CHD risk
- People with persistent negative mood may have an increased risk for coronary heart disease, research suggests. [BMJ 2008; Advance online publication]
- June 30, 2008
- CETP inhibitor anacetrapib shows initial promise
- The novel cholesteryl ester transfer protein inhibitor anacetrapib successfully increases high-density lipoprotein cholesterol and reduces low-density lipoprotein cholesterol with no apparent adverse side effects, report investigators. [Clin Pharmacol Ther 2008; Advance online publication]
- Statin efficacy in aortic stenosis may be disease stage related
- Statin treatment is effective at slowing progression of aortic valve sclerosis and mild but not moderate aortic stenosis, show results from a retrospective analysis. [Am J Cardiol 2008; Advance online publication]
- Adverse lipid profile linked to increased carotid IMT in obese children
- Researchers report that dyslipidemia but not the metabolic syndrome is associated with increased carotid intima-media thickness in obese children. [J Pediatr 2008; 153: 65-70.e1]
- No impact of race on chronic kidney disease outcomes
- Race does not appear to determine outcomes of patients with chronic kidney disease undergoing percutaneous coronary intervention, say US researchers who report similar mortality and major adverse cardiac event rates in African-American and White patients.
[Am Heart J 2008; 155: 1027-1032]
|
